An imaging system operable to generate an output image of a contrast agent injected in an imaged subject. The system includes a energy source, a detector and a display. The detector generates a plurality of radiological images of the imaged subject. The system also includes a computer having a memory in communication with a processor. The memory includes programmable instructions and including acquiring an image of the contrast agent in the imaged subject with a spectra of energy from the energy source detecting grayscale values of pixel data of the contrast agent in the image calculating a predicted thickness of the contrast agent relative to the plurality of grayscale values of pixel data of the contrast agent detected in the image and generating an output image comprising an illustration of the predicted thickness of the contrast agent for illustration ON the display.
