CKAP5-gene-silencing RNAi pharmaceutical composition

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专利权人:

Kyowa Hakko Kirin Co.;Kyowa Hakko Kirin Co., Ltd.; Ltd.;Dicerna Pharmaceuticals, Inc.

发明人:

Yabuuchi, Hayato,Kurihara, Kana,Yamada, Ayumi,Nakahashi, Keiko,Hatanaka, Kentaro,Tomura, Shiho

申请号：

AU2015269485

公开号：

AU2015269485A1

申请日:

2015.06.04

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The present invention provides: a composition for silencing a CKAP5 gene, the composition containing, as a drug, double-stranded nucleic acid that has a sequence of bases complementary to a sequence of at least 19 successive bases of mRNA of a CKAP5 gene having an antisense strand of any of SEQ ID NOS: 1-6, and lipid particles that contain a cationic lipid represented by formula (I) (in the formula, R

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/