LONBERG NILS,SRINIVASAN MOHAN,KORMAN ALAN J.,WANG CHANGYU,SELBY MARK J.,HENNING KARLA,HAN MICHELLE MINHUA,CHEN GUODONG,HUANG RICHARD,CHAKRABORTY INDRANI,HUANG HAICHUN,WONG SUSAN,LI HUIMING
申请号：
CL2016003136
公开号：
CL2016003136A1
申请日:
2016.12.05
申请国别(地区):
CL
年份:
2017
代理人:
摘要：
Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.La presente invención hace referencia a un anticuerpo aislado que se fija al receptor de TNF inducible por GITR, se mencionan ademas los ácidos nucleicos que lo codifican, composiciones que lo comprenden y uso de los anticuerpos en la preparación de un medicamento útil para tratar el cáncer.
