The present invention relates to a conjugate of cell penetrating peptide and an active ingredient; and its use. Specifically, a conjugate including a cell penetrating peptide which is a peptide comprising any one amino acid sequence of SEQ ID NO:2 to SEQ ID NO:178, a fragment of any one sequence of SEQ ID NO:2 to SEQ ID NO:178, or a peptide having above 80% homology with the above-mentioned sequences; and a composition comprising the same are disclosed.本發明係關於穿膜胜肽與有效成分之共軛物及該共軛物之使用。具體而言,揭示包括穿膜胜肽之共軛物及包含共軛物之組成物,該穿膜胜肽為包含SEQ ID NO:2至SEQ ID NO:178之任一種胺基酸序列之胜肽、SEQ ID NO:2至SEQ ID NO:178之任一序列之片段或具有與上述序列超過80%同源性之胜肽。