Transdermal Therapeutic System comprising of pouch (1) made of metallic foil, polymeric film, paper, laminates of these or a combination thereof which is sealed over the ages thermally, ultrasonically by application of pressure, gluing or a combination thereof, scraper layer (2) made of polymeric or metallic or non metallic powder or particles coated thereon, backing layer (3) which is provided on the top of the pouch, adhesive embedded with a drug mesh or net (4) at the bottom which is in contact with the pouch.