YANG, YI-YAN,WIRADHARMA, NIKKEN,HAUSER, CHARLOTTE, A. E.
申请号：
SG2013031992
公开号：
SG190019A1
申请日:
2011.10.31
申请国别(地区):
SG
年份:
2013
代理人:
摘要：
The present invention relates to antimicrobial peptides, to their use as antimicrobial agents and to their use in the treatment of (infectious) diseases, in particular infectious diseases caused by Gram-positive bacteria, Gram-negative bacteria, yeast or fungi. The present invention further relates to pharmaceutical compositions and kits comprising the antimicrobial peptides and to a method of lysing bacterial, yeast or fungal cells. The antimicrobial peptides consist of one of the following general formula: Wherein X is a hydrophobic amino acid, Y is a cationic amino acid, Z is an amino acid having a free thiol or thioether group, n is 2-4 and m is 0 or 1.
