CHOI, CHUL YUNG,최철웅,PAN, SANG O,반상오,KIM, JAE YONG,김재용,KANG, HU WON,강후원,LEE, GYU OK,이규옥,PARK, SUNG YOON,박성윤,SHIN, JA WON,신자원,CHOI, HAK JOON,최학준,JO, A RA,조아라,KIM, CHUN SUNG,김춘성,BAEK, JANG MI,백장미,KANG, G,CHOI, CHUL YUNGKR,PAN, SANG OKR,KIM, JAE YONGKR,KANG, HU WONKR,LEE, GYU OKKR,PARK, SUNG YOONKR,SHIN, JA WONKR,CHOI, HAK JOONKR,JO, A RAKR,KIM, CHUN SUNGKR,BAEK,
申请号：
KR1020160094491
公开号：
KR1017747010000B1
申请日:
2016.07.26
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention provides skate collagen peptide with anti-obesity activity, which effectively inhibits the expression of C/EBP and PPAR, which are adipocyte transcription factors, to reduce the differentiation into 3T3-L1 adipose precursor cells and to reduce the production of cholesterol and triglycerides in the blood； and has an effect of activating the inhibition on the lipid storage. The skate collagen peptide is obtained by firstly hydrolyzing one or more by-products selected from the body, cartilage, and skins produced during the processing of skate using Alcalase； and secondly hydrolyzing the firstly hydrolyzed product using protease type X.본 발명은 지방세포화 전사인자인 C/EBPβ와 PPARγ의 발현을 효과적으로 억제하여 3T3-L1 지방전구세포로의 분화를 감소시키고, 또한 혈액 내에 있는 콜레스테롤이나 중성지방의 생성을 감소시키고, 지질 축적 억제 활성 효과가 있는 항비만 활성을 갖는 홍어 콜라겐 펩타이드를 제공한다.
