Hands-free devices adapted for rapid brushing, cleaning and treating users' teeth are provided. In some embodiments, such a device comprises brushes for cleaning each of a user's teeth simultaneously. In some embodiments, such a device is generally U-shaped, accepting, cleaning and/or treating all of a user's teeth simultaneously. In some embodiments, a device is adapted to fit an individual user, based on 3-dimensional imaging. Example customized fluid jets within such devices are provided, introducing dentifrices and other treatments into tooth-conforming channels. In some embodiments, specialized handles are set forth, configured for hands-free use. Example methods and modes for such devices' use are also set forth. In some embodiments, compartments and cartridges with a proprietary form factor for delivering dentifrice and other treatments and for disposing of waste without mess are provided. In some embodiments, observational data are gathered, analyzed and serve as the basis for a treatment action plan.