Jun Luo,Emmanuel S. Antonarakis,Changxue Lu,Willian Isaacs
申请号：
US15505882
公开号：
US20170275673A1
申请日:
2015.08.25
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with prostate cancer. Disclosed herein are compositions and methods for detecting biological molecules and biomarkers associated with castration-resistant prostate cancer wherein such biological molecules and biomarkers comprise androgen-receptor splice variants that can be used to develop effective therapeutic regimens for prostate cancer patients. Disclosed herein are methods of using biological molecules and biomarkers related to androgen-receptor splice variants for assessing therapeutic resistance to drugs such as enzalutamide and abiraterone.
