MAKOOI-MOREHEAD, WILLIAM T.,BUEHLER, JOHN D.,LANDMANN, BRIAN R.
申请号：
HU0101517
公开号：
HU228498B1
申请日:
1999.04.01
申请国别(地区):
HU
年份:
2013
代理人:
摘要：
The present invention provides improved oral dosage form formulations of efavirenz that are useful in the inhibition of human immunodeficiency virus (HIV), the prevention or treatment of infection by HIV, and in the treatment of the resulting acquired immune deficiency syndrome (AIDS). In particular, the present invention relates to compressed tablets or capsules comprising efavirenz that contain one or more disintegrants that enhance the dissolution rate of the efavirenz in the gastrointestinal tract thereby improving the rate and extent of absorption of efavirenz in the body. The present invention also relates to the process of making such tablets or capsules.
