CHAN, YIN CHING,詹吟菁,CHEN, CHIN CHU,陈劲初,陳勁初,LEE, LI YA,李丽雅,李麗雅,CHEN, WAN PING,陈婉屏,陳婉屏
申请号:
TW104139886
公开号:
TWI595880B
申请日:
2015.11.30
申请国别(地区):
TW
年份:
2017
代理人:
摘要:
The invention provides an active substance for preventing hearing loss, preparation method thereof, pharmaceutical composition containing the same, and preparation method for the pharmaceutical composition. The preparation method for the active substance is provided to proceed with preparation by means of plate culture, flask culture, and fermentation tank culture to obtain active substance of Hericium erinaceus mycelium in powder configuration. The Hericium erinaceus mycelium powder is confirmed to have efficacy of preventing hearing loss through animal experiments.本發明提供一種預防聽力退化之活性物質、其製備方法、含其之醫藥組合物、及該醫藥組合物的製備方法。該活性物質之製備方法係透過平板培養、燒瓶培養、醱酵槽培養之方式製備,而得到粉末型態的猴頭菇菌絲體活性物質。該猴頭菇菌絲體粉末經動物實驗證實具有預防聽力退化的功效。