The present invention relates to an injectable anticancer composition for local administration comprising hydroxychloroquine. The anticancer composition shows an IC 50 value against sarcoma-180 cells, which is about 10 times lower than cisplatin, as determined by the MTT assay in vitro, suggesting that the anticancer composition has an excellent cytotoxic effect. Also, the anticancer composition shows dose-dependent effects against solid cancer induced by sarcoma-80 cells in vivo. In addition, the anticancer composition has the effect of extending the life expectancy of patients having ascites cancer induced by sarcoma-80 cells.本発明は、ヒドロキシクロロキン(hydroxychloroquine)を含む抗癌治療のための局所投与用注射剤組成物に関するもので、本発明による抗癌剤の組成物は、in vitroでMTT assayを通じたsarcoma180に対するIC50値がシスプラチンに比べて10倍くらい低い値を示し、優れた細胞毒性効果を有し、またin vivoでもsarcoma180によって誘発された固形癌に対して容量依存的な効果を現すだけでなく、sarcoma180によって誘発された腹水癌に対して寿命延長の効果がある。
