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ENZYMES FOR THE TREATMENT OF LIGNOCELLULOSICS, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM
专利权人:
VERENIUM CORPORATION
发明人:
STEGE, JUSTIN, T.,ABOUSHADI, NAHLA,DJORDJEVIC, GORDANA,BURKE, ELLEN,LUGINBUHL, PETER,DYCAICO, MARK,RICHARDSON, TOBY,POLAND, JOHN,HEFNER, YING,MILES, STACY, MARIE,CHANG, CATHY
申请号:
EP08728602
公开号:
EP2074136A4
申请日:
2008.01.30
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention provides polypeptides having a lignocellulolytic activity, e.g., a glycosyl hydrolase, a cellulase, an endoglucanase, a cellobiohydrolase, a beta- glucosidase, a xylanase, a mannanse, a xylosidase (e.g., a β- xylosidase), an arabinofuranosidase, and/or a glucose oxidase activity, polynucleotides encoding these polypeptides, and methods of making and using these polynucleotides and polypeptides. In one aspect, the invention provides polypeptides that can enzymatically process (hydrolyze) sugarcane bagasse, i.e., for sugarcane bagasse degradation, or for biomass processing, and polynucleotides encoding these enzymes, and making and using these polynucleotides and polypeptides. In one embodiment, the invention provides thermostable and thermotolerant forms of polypeptides of the invention. The polypeptides of the invention can be used in a variety of pharmaceutical, agricultural and industrial contexts for example, the invention provides a multi-enzyme system that can hydrolyze polysaccharides in a bagasse component of sugarcane processed in sugar mills. The invention provides enzymes for the bioconversion of lignocellulosic residues into fermentable sugars and these sugars can be used as a chemical feedstock for the production of ethanol and fuels, including biofuels such as bioethanol, biopropanol, biobutanol and biodiesels.Linvention concerne des polypeptides ayant une activité lignocellulosique, par exemple une glycosyl hydrolase, une cellulase, une endoglucanase, une cellobiohydrolase, une bêta-glucosidase, une xylanase, une mannase, une xylosidase (par exemple, une b-xylosidase), une arabinofuranosidase, et/ou une activité de glucose oxydase, des polynucléotides codant ces polypeptides, et des procédés de fabrication et dutilisation de ces polynucléotides et polypeptides. Dans un aspect, linvention propose des polypeptides pouvant traiter enzymatiquement (hydrolyser) de la bagasse de sucre de canne, à savoir, pour une dégradation de bagasse de sucre
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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