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Nitrogen-containing heterocyclic derivative having 11 beta-hydroxysteroid dehydrogenase type I inhibitory activity
专利权人:
Ltd.;Shionogi & Co.
发明人:
Ogawa, Tomoyuki,Nakatani, Takuji,Masuda, Koji
申请号:
AU2008252185
公开号:
AU2008252185B2
申请日:
2008.05.07
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Disclosed is a compound which is useful as an 11 β-hydroxysteroid dehydrogenase type I inhibitor. Specifically disclosed is a compound represented by the following formula (I) : (wherein ring A represents (II); ring B represents an optionally substituted heteroaryl (excluding an optionally substituted isoxazole) or an optionally substituted heterocycle; R represents a hydrogen or an optionally substituted alkyl; R represents -OR, -SR, a halogen, a halogenated alkyl or the like; R represents an optionally substituted alkyl or the like; R represents an optionally substituted alkyl or the like; R represents an optionally substituted alkyl or the like; R represents a hydrogen or the like; R and R independently represent a hydrogen or the like; R and R independently represent a hydrogen or the like; R represents an optionally substituted alkyl or the like; and m and p independently represent an integer of 1-3), a pharmaceutically acceptable salt thereof, or a solvate of any of them.
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