Phenolic hydrazone macrophage migration inhibitory factor inhibitors

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专利权人:

The Feinstein Institute for Medical Research

发明人:

Al-Abed, Yousef

申请号：

AU2007231012

公开号：

AU2007231012B2

申请日:

2007.03.23

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

Provided are various compounds of Formula (I): Also provided are pharmaceutical compositions comprising the above compounds. Additionally, methods of inhibiting macrophage migration inhibitory factor (MIF) activity in a mammal are provided, as are methods of treating or preventing inflammation in a mammal. Further provided are methods of treating a mammal having sepsis, septicemia, and/or endotoxic shock. Also provided are methods of treating a mammal having an autoimmune disease, and methods of treating a mammal having a tumor.

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