John D. Price;Mary C. Spencer;Thomas Piccariello;Scott B. Palmer;Michaela E. Mulhare;Robert Oberlender
发明人:
Thomas Piccariello,Scott B. Palmer,John D. Price,Robert Oberlender,Mary C. Spencer,Michaela E. Mulhare
申请号:
US12316259
公开号:
US08236787B2
申请日:
2008.12.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Embodiments of the present disclosure include a coordination complex, comprising a first biologically active moiety, a second biologically active moiety, and a metal, wherein the first biologically active moiety and second biologically active moiety are bound to the metal by covalent coordination bonds, and wherein the first biologically active moiety and second biologically active moiety are different. These complexes may enhance the pharmacodynamic properties of biologically active moieties.