BOUCKENOOGHE, THOMAS,BERTHOLET, PAULINE,DELORME, BRUNO
申请号:
CA2974593
公开号:
CA2974593A1
申请日:
2016.02.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The invention relates to a matrix in ball form comprising cross-linked fibrinogen, the matrix being free from fibrin, as well as to a method for preparing such a matrix, comprising the following steps: (a) providing an initial composition comprising fibrinogen and a platelet factor, (b) injecting said initial composition into an oil heated to a temperature of 50 °C to 80 °C so as to form an emulsion, (c) mixing the emulsion thus obtained at a temperature of 50 °C to 80 °C until a matrix in ball form is obtained, and (d) isolating the matrix thus obtained. The matrix is used as a cell carrier.