C. Frank Bennett,Kenneth W. Dobie,Susan M. Freier,Stanley T. Crooke
申请号：
US13566922
公开号：
US20130035370A1
申请日:
2012.08.03
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed herein are compounds, compositions and methods for modulating the expression of LMNA in a cell, tissue or animal. Also provided are methods of target validation. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders. Further provided are methods of identifying cis splicing regulatory elements of a selected mRNA using the disclosed compounds.
