GENETIC POLYMORPHISMS ASSOCIATED WITH PSORIASIS, METHODS OF DETECTION AND USES THEREOF

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专利权人:

Yonghong LI;Michele CARGILL;Steven SCHRODI;Ann BEGOVICH;Monica CHANG

发明人:

Yonghong LI,Ann BEGOVICH,Monica CHANG,Michele CARGILL,Steven SCHRODI

申请号：

US13080458

公开号：

US20120082678A1

申请日:

2011.04.05

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention is based on the discovery of genetic polymorphisms that are associated with psoriasis and related pathologies. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, including groups of nucleic acid molecules that may be used as a signature marker set, such as a haplotype, a diplotype, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.

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