A cooling device for placement against a body part or object includes a shell member having an outer face and an inner face disposed against a surface to be cooled. A first cooling substrate is disposed within the shell member and is an absorbent web having a generally uniform application of a first cooling composition applied thereto, the cooling composition activated by contact with an aqueous liquid. An aqueous liquid source is disposed within the shell member and is separated from the first cooling substrate by a barrier member. The device is activated by manual manipulation to breach the barrier member causing liquid from the liquid source to move within the interior space of the shell member to contact and activate the cooling composition whereby a cooling reaction is generated.