SUN, JEONGHOON,TAM, LEI-TING TONY,HAN, HUIQUAN,KWAK, KEITH SOO-NYUNG,ZHOU, XIAOLAN,LU, JOHN
申请号:
HK15103990.7
公开号:
HK1203384A
申请日:
2015.04.24
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.