A device and method for opening blood vessel blockages, such as chronic total occlusions, is disclosed. The device has drilling unit and a stationary unit having a plurality of curved alignment structures along its outer edge for bracing against the inner surface of a blood vessel wall. A torque-transmitting member (drive shaft) is disposed within the stationary unit and extends into the rotating drilling unit. The curved alignment structures along the outer surface of the device help to centrally align the device within the blood vessel, thereby preventing the device from deflecting and puncturing blood vessel walls. The drilling unit that has a plurality of loops on its distal tip, located at the distal region of the drilling unit. These loops break apart occlusions as the device advances and rotates through the blood vessel.
