BAGLE, LEENA SHRIRAM,BHUPENDER BHALLA, AMARDEEP SINGH,GARCIA, MIGUEL ANGEL,HU, LEI,KHANDKE, LAKSHMI,YANG, CINDY XUDONG,ANDERSON, ANNALIESA SYBIL,PRASAD, AVVARI KRISHNA
申请号:
CA3042993
公开号:
CA3042993A1
申请日:
2017.11.02
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The invention relates to immunogenic compositions comprising a capsular polysaccharide (CP) from Streptococcus agalactiae, commonly referred to as group B streptococcus (GBS), conjugated to a carrier protein, and optionally including an aluminum-based adjuvant. The invention further relates to methods for inducing an immune response in subjects against GBS and/or for reducing or preventing invasive GBS disease in subjects using the compositions disclosed herein. The resulting antibodies can be used to treat or prevent GBS infection via passive immunotherapy.