The Governing Council of the University of Toronto
发明人:
GRAY-OWEN, Scott,GAUDET, Ryan,MALOTT, Rebecca
申请号:
EP15848249
公开号:
EP3204014B1
申请日:
2015.10.09
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Novel methods and uses for modulating immune responses are provided. The methods and uses involve the use of a TIFA activator such heptose-1,7-5 bisphosphate or an analog or derivative thereof. The methods may be used to activate, inhibit or otherwise modify an immune response so as to either prevent or treat infectious or inflammatory diseases or cancer. Also provided are methods to identify compounds capable of modulating immune responses.