Genus Oncology, LLC; LLC;Dana-Farber Cancer Institute, Inc.;Genus Oncology
发明人:
Kufe, Donald W.,Kharbanda, Surender
申请号:
AU2010253834
公开号:
AU2010253834B2
申请日:
2010.05.27
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention provides for peptides from the MUCl cytoplasmic domain and methods of use therefor. These peptides can inhibit MUCl oligomerization, inhibit the interaction of MUCl with NF -KB or a STAT, and block inflammatory response mediated by NF-κB or STAT signaling.