Bispecific antigen binding molecules

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专利权人:

ROCHE GLYCART AG

发明人:

Klein, Christian,Bruenker, Peter,Umana, Pablo,Fauti, Tanja,Jaeger, Christiane,Auer, Johannes,Schaefer, Wolfgang,Sustmann, Claudio

申请号：

NZ72114712

公开号：

NZ721147A

申请日:

2012.08.21

申请国别(地区):

NZ

年份:

2020

代理人:

摘要：

Discloses bispecific antigen binding molecules comprising two Fab fragments specific to a first antigen and a second Fab fragment specific to a second antigen fused to a first Fc domain subunit. One of the Fab fragments is a crossover fab fragment with a VH-CL/VLCH1 arrangment. The bispecific antigen binding molecule does not comprise a single chain Fab fragment.

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中国工程科技知识中心

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