PETIT, Robert,WALLECHA, Anu,CHEN, Zhisong,BERZOFSKY, Jay A.,KHLEIF, Samir
申请号:
EP15758226
公开号:
EP3113794A4
申请日:
2015.03.05
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention is directed to methods for increasing T-cell effector cell to regulatory T cell ratio. The invention is further directed to methods of treating, protecting against, and inducing an immune response against a tumor, comprising the step of administering to a subject a recombinant Listeria strain, comprising a fusion peptide that comprises an LLO fragment and tumor-associated antigen.