A patient support apparatus, such as a mattress, has multiple air sources to inflate air bladders of the apparatus. In one embodiment, a first air source provides air to one or more main support bladders and a second air source provides air to one or more microclimate bladders when a control system of the patient support apparatus operates according to a first mode of operation. The first and second air sources provide air to a turn bladder when the control system operates according to a second mode of operation. In another embodiment, a first air source provides air to at least one main support bladder and to at least one microclimate bladders. A second air source is dedicated for inflating at least one turn bladder.
