MODIFIED ADENOVIRUS HEXON PROTEIN AND USES THEREOF

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专利权人:

发明人:

Soumitra Roy,James M. Wilson

申请号：

US14719893

公开号：

US20160102295A1

申请日:

2015.05.22

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides a method of altering the specificity of an adenovirus vector. The method involves providing an adenovirus having a capsid with a modified adenovirus hexon protein. The modified adenovirus has a capsid comprising a hexon protein with a deletion in hypervariable region 1 and/or hypervariable region 4 of the hexon and an insert of an exogenous molecule therein.

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中国工程科技知识中心

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http://www.ckcest.cn/home/