A method for determining effectiveness of treatment of patients, carried out using different matched with each other scientific methods of treatment, wherein the effectiveness of treatment of patients determine execution system integrated serial studies and analysis through multiobjective integrated comparative evaluation of the dynamics of the patients comprising aggregated results of the clinical, laboratory and instrumental investigations containing their qualitative esearch based scales and test consisting of rank evaluation of the dynamics of the patients with the subjective and objective data, wherein the determination is performed by comparing the effectiveness of treatment of patients on the basis of the absolute and exhaustive number of comparisons to be determined according to the determined relationship: somewhere total number of patients exhaustive comparisons (groups of patients), - the total number of patients involved in the study (groups of patients) to be compared ! - m-factorial - a number equal to the product of all integers from 1 (or, equivalently, from 2) to chislavklyuchitelno of: - the number of patients (patient groups) involved in series between a pair-wise comparison simultaneously ! - k-factorial - a number equal to the product of all integers from 1 (or, equivalently, 2) to this chislavklyuchitelno: (-)! - (mk) -faktorial - a number equal to the product of all integers from 1 (or, equivalently, 2) to a given number (mk) and including: