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ANIMAL MODEL FOR GENERATING A STEREOTYPE OF FOCAL ONSET SEIZURES
专利权人:
CHUNG SHAN MEDICAL UNIVERSITY;CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL
发明人:
YUE-LOONG HSIN,SYU-JYUN PENG,CHENG-SIU CHANG,FU-YUAN SHIH
申请号:
US16283736
公开号:
US20200178877A1
申请日:
2019.02.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
It includes the steps of (1) preparing step; (2) anesthetizing step; (3) electrodes installing step; and (4) focal onset seizures inducing step. First, a live animal is anesthetized. The electrodes are installed on a working zone of its brain. A first chemical liquid is injected beneath the cerebral cortex of this animal. At two different times, a first electric stimulation and a second electric stimulation are activated by the controller respectively so as to generate a first and a second focal onset seizure accordingly. Thus, it can generate focal onset seizures. It is easy to change the electric stimulation position, numbers and type. In addition, the survival rate of a larger-sized animal after anesthesia is higher.
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