CHEKAL Brian Patrick,CHEKAL Brian Patrick,IDE Nathan D.,IDE Nathan D.
申请号：
SI201430929
公开号：
SI2958916T1
申请日:
2014.02.08
申请国别(地区):
SI
年份:
2018
代理人:
摘要：
This invention relates to the crystalline free base of acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, formula (1) having improved properties, to pharmaceutical compositions and dosage forms comprising the free base, and to methods for making and using such compounds, compositions and dosage forms in the treatment of cell proliferative diseases, such as cancer.
