The invention provides methods of treating a human patient having a Lidocaine-lneffective Condition or a hypokalemic condition by administration of either a potassium-elevating agent or potassium, alone or in combination with additional agents. Patients amenable to the treatment regimens described herein include those having a diagnosis of a hypokalemic condition, disorder of attention, Asperger Syndrome, Sensory Overstimulation Syndrome (SOS), Sensory Processing Disorder, Sensory Integration Disorder, Fibromyalgia, various pain syndromes and/or Premenstrual Syndrome. The invention additionally features pharmaceutical compositions and kits for the treatment of such conditions.