PROCÉDÉ DE PRODUCTION DE POLYPEPTIDE RECOMBINÉ

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

TABUCHI, HISAHIRO,SUGIYAMA, TOMOYA

申请号：

EP12768095

公开号：

EP2695947A4

申请日:

2012.03.30

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

Provided is a method capable of producing a protein at a high level using a cultured animal cell, comprising culturing a cell that expresses APES (Antibody Production Enhancing Sequence) and into which a DNA encoding a desired polypeptide has been introduced, thereby producing the desired polypeptide. APES contains a nucleotide sequence related to NfkBia and has a function of decreasing the intracellular expression of NfkBia.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/