Kwang Gill Lee;Joo Hong Yeo;Seok Woo Kang;Hae Yong Kweon;Jin Kim;Soon Ok Woo;You Young Jo;Chan Hum Park;Sang-Mi Han;Chun Hwoi Kim
发明人:
Hae Yong Kweon,Kwang Gill Lee,Seok Woo Kang,Joo Hong Yeo,You Young Jo,Soon Ok Woo,Sang-Mi Han,Chan Hum Park,Jin Kim,Chun Hwoi Kim
申请号：
US12493277
公开号：
US08500808B2
申请日:
2009.06.29
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided is an artificial eardrum using silk protein and a method of fabricating the same. The artificial eardrum is fabricated in the form of a silk membrane by desalinating and drying silk protein (or silk fibroin) or a silk protein complex solution obtained after removal of sericin from a silkworm cocoon or silk fiber. Thus, regeneration of an eardrum perforated due to disease or a sudden accident is stimulated, a boundary of the regenerated eardrum is clean and biocompatibility and transparency are increased. In addition, the artificial eardrum may be fabricated using the silk protein or silk protein complex solution obtained from a silkworm cocoon alone or mixed with collagen, alginic acid, PEG or pluronic 127.
