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MONOCLONAL ANTIBODY DIRECTED TO FGFR1
专利权人:
MERCK PATENT GMBH
发明人:
CHRISTEL IFFLAND,CHRISTINA ESDAR,XINYAN ZHAO,QI AN,JOHANNES YEH,GANG HAO,LARS TOLEIKIS,VANITA SOOD,DAVID NANNEMANN,ROBIN LYTLE,BJOERN HOCK
申请号:
US16462961
公开号:
US20190367620A1
申请日:
2017.11.21
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to antibodies with specificity for FGFR1. More particularly, the invention relates to monoclonal antibodies that bind specifically to and neutralize human, macaque and mouse forms of FGFR1 with high affinity. The invention also relates to nucleic acids encoding said antibodies, vectors for expression of these nucleic acids, and host cells for producing said antibodies. Further, the invention relates to the use of said antibodies in the diagnosis and/or treatment of cancers.
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