BIFTU, TESFAYE,CHEN, PING,COX, JASON M.,WEBER, ANN E.
申请号:
CA2742783
公开号:
CA2742783C
申请日:
2009.11.11
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention is directed to novel substituted aminotetrahydropyransof structural formula I which are inhibitorsof the dipeptidyl peptidase-IV enzyme and which are useful in the treatment orprevention of diseases in which the dipeptidyl peptidase-IV enzyme isinvolved, such as diabetes and particularly Type 2 diabetes. The invention isalso directed to pharmaceuticalcompositions comprising these compounds and the use of these compounds andcompositions in the prevention or treatmentof such diseases in which the dipeptidyl peptidase-IV enzyme is involved.