Da Rocha E Lima, Luis Mauricio Trambaoli,Rosado, Luiz Henrique Guerreiro,Guterres, Mariana Fernandes De Avila Netto,Ferreira, Bruno Melo Vieira Gonçalves
申请号：
AU2016371260
公开号：
AU2016371260A1
申请日:
2016.12.14
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present disclosure concerns non-agglomerating bioconjugates of amylin, amylin-mimetic compounds, and combinations comprising the same, wherein said bioconjugate contains at least one acyl unit. Methodology of making and using are provided herein. In some embodiments, an instant non-agglomerating amylin bioconjugate can be used for treating a disease associated with a lack of natural production of amylin and/or deposition or accumulation of extracellular amyloid fibers, which contribute to the dysfunction or failure of systemic organs such as the pancreas or the brain.
