Solid forms comprising (+)-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisinoline-1,3-dione, compositions thereof, and uses thereof
Hon-Wah Man;Peter H. Schafer;George W. Muller;Chuansheng Ge;Jean Xu
发明人:
George W. Muller,Peter H. Schafer,Hon-Wah Man,Chuansheng Ge,Jean Xu
申请号:
US12945800
公开号:
US08093283B2
申请日:
2010.11.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Solid forms comprising (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions comprising the solid forms, methods of making the solid forms and methods of their use are disclosed. The methods include methods of treating and/or preventing disorders ameliorated by the reduction of levels of TNF-α or the inhibition of PDE4.