An image processing system connected to an endoscope and processing in real-time endoscopic images to identify suspicious tissues such as polyps or cancer. The system applies preprocessing tools to clean the received images and then applies in parallel a plurality of detectors both conventional detectors and models of supervised machine learning-based detectors. A post processing is also applied in order select the regions which are most probable to be suspicious among the detected regions. Frames identified as showing suspicious tissues can be marked on an output video display. Optionally, the size, type and boundaries of the suspected tissue can also be identified and marked.
