PROBLEM TO BE SOLVED: To provide a simple and inexpensive method of sterilizing and testing the integrity of dialyzers (such as hollow fiber dialyzers.SOLUTION: A method of combined sterilization and integrity testing of dialyzers such as hollow fiber dialyzers comprises steps of: treating the dialyzer with a sterilization fluid for sterilizing at least the blood-side compartment of the dialyzer and for wetting a dialysis membrane or a hollow fiber dialysis membrane of the dialyzer with the sterilization fluid and carrying out an integrity testing of the dialysis membrane wetted with the sterilization fluid. The sterilization fluid is selected from aqueous solutions containing peroxide and/or ozone, the peroxide being selected from peroxides which disintegrate into water, oxygen and/or volatile organic compounds, and from aqueous solutions containing chlorine, bromine and/or iodine.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】滅菌し、且つ透析機群(例えば、中空糸型透析機群)の完全性をテストする、簡易で且つ安価な方法を提供する。【解決手段】滅菌と中空糸型透析機等の透析機の完全性をテストする方法は、透析機の少なくとも血液側区分を滅菌すると共に透析膜又は中空糸型透析膜を湿潤させるための、滅菌流体をもって透析機を処理するステップと、滅菌流体で湿潤された該透析膜の完全性テストを行うステップとを備える。滅菌流体は、過酸化物及び/又はオゾンを含む水溶液群であって、過酸化物は、水、酸素及び/又は揮発性有機化合物に分解する過酸化物群から選択されるものと、及び、塩素、臭素及び/又はヨウ素を含む水溶液群とから選択される。【選択図】なし
