HONG, HYO JEONG,MAENG, CHEOL-YOUNG,YANG, GI-HYEOK,JANG, MEONG HEE,OH, MEE SOOK,SONG, JIN-SOO,JANG, YOUNG KUG
申请号：
CA2492671
公开号：
CA2492671C
申请日:
2003.03.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
A humanized antibody is produced by process comprising the steps of: (a)selecting a specificity determining residue (SDR) of the complementaritydetermining region (CDR) of murine monoclonal antibody heavy chain and lightchain variable regions； and (b) grafting said SDR to at least one of thecorresponding amino acid sequences in human antibody variable regions.
