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RAS INHIBITORY PEPTIDES AND USES THEREOF
专利权人:
发明人:
VERDINE GREGORY L,MCGEE JOHN HANNEY
申请号:
IN201617040161
公开号:
IN201617040161A
申请日:
2016.11.24
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention provides peptides comprising a sequence of X-6X-5X-4X-3X-2X- 1X1PX3X4PX6X7PGX10X11AX13X14X15X16LX18X19X20X21X22X23LX25X26YLX29X30X31X32 wherein the amino acids X-6, X-5, X-4, X-3, X-2, X-1, X1 X3, X4, Χ6, Χ7, Χ10, X11, X13, X14, X15, X16, X18, X19, X20, X21, X22, X25, X26, X29, X30, X31, and X32 are as defined herein. The present invention further provides pharmaceutical compositions comprising the peptides and methods of using the peptides. Also provided are methods of screening a library of peptide dimers using a peptide dimer display technology.
来源网站:
中国工程科技知识中心
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