The invention provides a monoclonal antibody or an antigen binding fragment thereof comprising an antigen binding site that binds specifically to a 161P2F10B protein (SEQ ID NO:4), wherein the monoclonal antibody is H16-7.213, H16-9.69, H16-1.52, Ha16-1(1)23, Ha16- 9.44, H16-1.67, Ha16-1(3,5)36, H16-1.86, Ha16- 9.10, H16-9.33, H16-1.68, Ha16-1(1)11, Ha16- 1(3,5)18, Ha16-i(2,4)4, Ha16-1(3,5)56, H16-1.93, H16-7.8, Ha16-1(3,5)27.1, H16-1.61, H16-1(3,5)5, H16-7.200, Ha16-1(3,5)42, H16-9.65, H16-1.29, H16-3.4, H16-1.92, Ha16-1(3,5)19, or Ha16-1.80 as shown in Figures 2 and 3. The invention further provides various uses of said antibody.
