Disclosed herein are various embodiments of methods, systems and devices for detecting atrial fibrillation (AF) in a patient. According to one embodiment, a patient places his or her left and right hands around left and right electrodes and a hand-held atrial fibrillation detection device acquires an electrocardiogram (ECG) from the patient over a predetermined period of time such as, by way of example, one minute. After acquiring the ECG from the patient, the device processes and analyzes the ECG and makes a determination of whether the patient has AF. The device may further be configured to provide a visual or audio indication of whether the patient has AF, or does not have AF. The device may be employed in a health care providers office without the need for complicated or expensive diagnostic equipment, and is capable of providing an on-the-spot and low-cost diagnosis of AF. The device may further be connected to a physicians computer in the office, which may be configured to store the results of the analysis and the patients ECG, and which may further be configured to carry out additional processing and analyses of the acquired and processed data. Moreover, the physicians computer may be operably connected to a remote server configured to store, process and analyze the ECG and the results provided by the hand-held device.
