A system for positioning and inserting insertion means into tissue includes an insertion head and an inserter. The insertion head includes a base with a lower side positionable on tissue and an insertion means movably mounted by the base, which is movable from a protective position where a free end of the insertion means is short of the lower side, into an insertion position where the free end protrudes beyond the lower side of the base. The inserter includes an inserter casing having a lower side with an opening for the insertion head a holding means, coupled to the inserter casing for holding the insertion head in an initial position a drive configured to move the insertion head out of the initial position in an advancing direction and an activating member movable relative to the holding means and operable such that the insertion means is moved into the insertion position.