SPIRO[3H-INDOLE-3,2-PYRROLIDIN]-2(1H)-ONE DERIVATIVES AND THEIR USE AS MDM2-P53 INHIBITORS

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专利权人:

BOEHRINGER INGELHEIM INTERNATIONAL GMBH

发明人:

申请号：

EP15716495.5

公开号：

EP3129380B1

申请日:

2015.04.10

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention includes formula (I), wherein group R1 has in claim 1 to R7, V, W, X, Y, n and q and defines, the application MDM2-p53 interactions of its inhibitor, these pharmaceutical compositions contain this kind of compound, their purposes as drug, especially as treating or preventing tumor disease and synthetic intermediate.

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