Pharmaceutical composition for treating or preventing cancer that induces dendritic cell-like differentiation from monocytes and enhances anti-cancer immune activity

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专利权人:

国立大学法人;岡山大学

发明人:

公文 裕巳,那須 保友,渡部 昌実,柏倉 祐司

申请号：

JP2010505881

公开号：

JP5447861B2

申请日:

2009.03.24

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

According to the present invention, a composition for inducing or activating dendritic cell-like cells so as to treat or prevent cancer by immunotherapy is provided. Specifically, the following is provided: an agent for activating cancer immunity, which comprises, as an active ingredient, the following REIC protein: (a) a protein consisting of the amino acid sequence shown in SEQ ID NO: 2； or (b) a protein consisting of an amino acid sequence derived from the amino acid sequence shown in SEQ ID NO: 2 by substitution, deletion, or addition of one or more amino acid(s) and having the activity of inducing differentiation from monocytes into dendritic cell-like cells.

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中国工程科技知识中心

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http://www.ckcest.cn/home/