A refrigerator with a sterilization device. The sterilization device mounted at an upper surface of a storage chamber includes a housing formed, at a front surface thereof, with an ion outlet while being formed, at a base surface thereof, with an air inlet, an ion generating unit arranged in rear of the ion outlet to generate ions, a blast unit slantingly arranged at a position adjacent to the air inlet, and a guide portion formed to protrude at an upper surface of the housing which faces the blast unit, thereby enabling improvement in sterilization efficiency.