PURPOSE: A composition including a polyacetylene compound or extract of Petrosia sp. is provided to have growth-suppressing activation effect to cancer cells, thereby being used as a pharmaceutical composition for treating and preventing cancer cells.CONSTITUTION: A composition including a polyacetylene compound or extract of Petrosia sp. is represented by chemical formula 1. The polyacetylene-based compound has three hydroxy groups. The polyacetylene compound has hydroxy groups at the third, 16th, and 28th positions. A pharmaceutical composition for treating and preventing cancer contains the compound or a pharmaceutically acceptable salt as an active ingredient. The amount of the compound is 0.1-50 wt%, based on the total weight of the composition.COPYRIGHT KIPO 2013본 발명은 폴리아세틸렌 화합물 또는 해면동물 페트로시아(Petrosia sp.) 추출물을 유효성분으로 함유하는 암 질환의 예방 및 치료를 위한 조성물에 관한 것으로, 상세하게는 본 발명의 신규 화합물 또는 페트로시아 추출물은 다양한 암세포주에 대해 성장 억제 활성 효과를 나타냄을 확인함으로써, 암 질환의 예방 및 치료에 유용한 약학 조성물로 이용될 수 있다.